Product Identification
【Product Name】Bronopol；溴硝醇
【Synonyms】2-Bromo-2-nitro-1,3-propanediol
【CAS】52-51-7
【Formula】C3H6BrNO4
【Molecular Weight】199.99
【EINECS】200-143-0
【RTECS】TY3385000
【RTECS Class】Agricultural Chemical and Pesticide; Drug; Primary Irritant
【Merck】13,1432
【Beilstein/Gmelin】1705868
【Beilstein Reference】4-01-00-02501
【EC Index Number】603-085-00-8
【EC Class】Harmful; Irritant; Dangerous for the Environment

Physical and Chemical Properties
【Appearance】White crystals. May detonate under strong shock.
【Solubility in water】280 mg/L
【Melting Point】130-133℃
【Boiling Point】388℃
【Vapor Pressure】1.5E-6 (25℃)
【Density】1.91 g/cm3
【pKa/pKb】12.01 (pKa)
【Partition Coefficient】1.72
【Heat Of Vaporization】69.9 kJ/mol
【Usage】Preservative in cosmetics and toiletries. Bactericide.

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
【Handling】Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames.

Hazards Identification
【Inhalation】Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Causes irritation of the mucous membrane and upper respiratory tract. May cause burning sensation in the chest.
【Skin】May be harmful if absorbed through the skin. May cause irritation and dermatitis. May cause cyanosis of the extremities.
【Eyes】Contact may cause severe eye irritation and possible eye damage. May cause chemical conjunctivitis and corneal damage.
【Ingestion】Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
【Hazards】May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form. May re-ignite after fire is extinguished.
【EC Risk Phrase】R21/22 37/38 41 50
【EC Safety Phrase】S 26 37/39 61
【UN (DOT)】3241

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear safety glasses and chemical ggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
【Exposure Effects】The toxological properties of this substance have not been fully investigated.
【Poison Class】3

Fire Fighting Measures
【Flash Point】170℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable solid. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
【Fire Potential】Flammable/combustible material.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Sweep up, then place into a suitable container for disposal. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents, strong reducing agents, strong bases, acid chlorides, acid anhydrides, moisture.
【Decomposition】Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide, nitrogen.
【Combustion Products】Fire may produce irritating and/or toxic gases.

Transport Information
【UN Number】3241
【Hazard Class】4.1
【Packing Group】III
【HS Code】2905 59 99