Product Identification
【Product Name】Guanidine thiocyanate
【Synonyms】Guanidine isothiocyanate 硫氰酸胍
【CAS】593-84-0
【Formula】C2H6N4S
【Molecular Weight】118.16
【EINECS】209-812-1
【RTECS】XL1225000
【RTECS Class】Other
【Beilstein/Gmelin】3563461
【Beilstein Reference】4-03-00-00299
【EC Index Number】615-004-00-3
【EC Class】harmful
Physical and Chemical Properties
【Appearance】White powder.
【Solubility in water】1420 g/L (20℃)
【Melting Point】118℃
【Density】1.29 g/cm3 (20℃)
【Usage】A powerful chaotropic agent.
First Aid Measures
【Ingestion】Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.
Handling and Storage
【Storage】Do not store in direct sunlight. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light. Discard contaminated shoes.
Hazards Identification
【Inhalation】May cause effects similar to those described for ingestion. Exposure produces central nervous system depression. Causes irritation of mucous membrane. At high concentrations, isocyanates affect mucous membranes of the respiratory tract and may lead to fatal pulmonary edema. Exposure to low and often even unmeasurable isocyanate concentration results in sensitization. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
【Skin】Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. In the presence of moisture, this material may be absorbed through the skin. If absorbed, may cause symptoms similar to those for ingestion.
【Eyes】Causes eye irritation. May cause conjunctivitis, ulceration and turbidity of the cornea.
【Ingestion】May cause irritation of the digestive tract. May cause liver and kidney damage. Ingestion of thiocyanates may cause disorientation, weakness, low blood pressure, confusion, psychotic behavior, muscular spasms, convulsions, and death.
【Hazards】Contact with metals may evolve flammable hydrogen gas.
【EC Risk Phrase】R 20/21/22 32
【EC Safety Phrase】S 13
【UN (DOT)】2811
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】May cause liver and kidney damage. Effects may be delayed. May cause lung damage. Repeated or prolonged exposure may cause allergic reactions in sensitive individuals. Inhalation of product may aggravate existing chronic repiratory problems such as asthma, emphysema or bronchitis.
【Poison Class】3
Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Accidental Release Measures
【Small spills/leaks】Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong bases, strong oxidizing agents, water, acids.
【Decomposition】Hydrogen cyanide, nitrogen oxides, carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide, cyanide fumes, hydrocarbons.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
【UN Number】2811
【Hazard Class】6.1
【Packing Group】I; II; III
【HS Code】2925 20 00