Product Identification
【Product Name】PAS  对氨基水杨酸
【Synonyms】4-Aminosalicylic acid
【CAS】65-49-6
【Formula】C7H7NO3
【Molecular Weight】153.13999999999999
【EINECS】200-613-5
【RTECS】VO1225000
【RTECS Class】Drug; Mutagen; Primary Irritant
【Merck】13,476
【Beilstein/Gmelin】473071
【Beilstein Reference】4-14-00-01967

Physical and Chemical Properties
【Appearance】Minute crystals from alc. Odorless, or has slight acetous odor.
【Solubility in water】2 g/L
【Melting Point】150℃
【Boiling Point】347℃
【Density】1.545 g/cm3
【pKa/pKb】3.25 (pKa)
【Partition Coefficient】.4
【Usage】Industrial preservative.

First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from light. Store under an inert atmosphere.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Handle under an inert atmosphere. Store protected from air.

Hazards Identification
【Ingestion】May cause irritation of the digestive tract.
【Inhalation】May cause respiratory tract irritation.
【Skin】May cause skin irritation.
【Eyes】Causes eye irritation.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Place under an inert atmosphere.

Stability and Reactivity
【Disposal Code】4
【Incompatibilities】Air.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information
【HS Code】2922 50 00